Study on Tongue Image and Formation of Mucus Plug in Airway of Mycoplasma Pneumoniae Pneumonia in Children
10.19879/j.cnki.1005-5304.202405262
- VernacularTitle:肺炎支原体肺炎患儿舌象与气道黏液栓形成的研究
- Author:
Li PENG
1
;
Lili ZHONG
;
Qinghua LIU
;
Baixiang LIU
;
Lin LIN
Author Information
1. 湖南省人民医院(湖南师范大学附属第一医院)儿童医学中心,儿童呼吸病学湖南省重点实验室,湖南 长沙 410005
- Keywords:
mycoplasma pneumoniae pneumonia;
tongue image;
mucus plug;
children
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(12):151-155
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of tongue diagnosis in the evaluation of airway mucus plug formation in mycoplasma pneumoniae pneumonia(MPP).Methods Totally 418 MPP children with MPP were included in this study.According to the formation of mucus plug under the microscope,the children with MPP were divided into mucus plug group(n=108)and non-mucus plug group(n=310).The purpose of this study was to compare the tongue features(tongue color,coating color,coating quality,tongue fluid)and levels of related inflammatory factors C-reactive protein(CRP),lactate dehydrogenase(LDH),interleukin(IL)-6,etc between the two groups,and to explore the role of tongue examination in evaluating the formation of mucus plugs in MPP.Results The tongue color of MPP mucus plug group was mainly crimson tongue,the coating color was mainly yellow fur,the coating quality was mainly thick greasy coating,and the tongue fluid was mainly fluid.The tongue image score of MPP mucus plug group was significantly higher than that of non-mucus plug group(P<0.05).Multivariate logistic regression analysis showed that CRP,IL-6,IL-17,γ interferon(IFN-γ),LDH and tongue total score were independent risk factors for mucus plug formation in MPP.The results of receiver operating characteristic(ROC)curve showed that the area under the curve(AUC)of CRP,tongue image score,LDH,IL-6,IL-17 and IFN-γ to predict the formation of mucus plug in MPP were 0.893,0.830,0.783,0.794,0.627 and 0.602,respectively.The optimal cut-off values were 37.445(mg/L),4.5(pionts),358.673(U/L),27.174(pg/mL),4.855(pg/mL)and 26.427(pg/mL),respectively.The AUC of MPP mucous plug formation was 0.930,the sensitivity was 0.907,and the specificity was 0.827.Conclusion There are differences in tongue image characteristics in MPP children with mucus plug formation.Total tongue image score can better predict mucus plug formation in MPP,and combined analysis has greater value in predicting MPP mucus plug formation.
