Research Progress in Pharmacological Effects,Toxicity and Clinical Application of Matrine
10.19879/j.cnki.1005-5304.202310213
- VernacularTitle:苦参碱药理作用、毒性及临床应用研究进展
- Author:
Qichao SUN
1
;
Yunhong KANG
;
Jing XU
;
Qing MIAO
Author Information
1. 黑龙江中医药大学附属第一医院,黑龙江 哈尔滨 150040
- Keywords:
matrine;
pharmacological effects;
toxicity;
clinical application
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(11):191-196,后插1
- CountryChina
- Language:Chinese
-
Abstract:
Matrine has various pharmacological effects,including antitumor,anti-inflammatory,and antibacterial effects,which is an adjuvant drug widely used in clinical cancer chemotherapy.However,due to the fact that matrine is both an active and toxic component of Chinese materia medica,its clinical safety is particularly important.This article reviewed the research progress in the pharmacological effects of matrine from the aspects of anti-inflammatory,anticancer,antibacterial and antiviral,cardiovascular protection,neuroprotection,liver and kidney protection,and detoxification.It also summarized its toxicity and clinical application research,aiming to provide reference for the rational use of matrine.
