Research advances in early diagnosis and screening of colorectal cancer based on fecal testing
10.12354/j.issn.1000-8179.2024.20240869
- VernacularTitle:结直肠癌早期粪便筛查标志物的研究进展
- Author:
Long YUANZHAOYUN
1
;
Yan ZHONGSHENG
Author Information
1. 甘肃中医药大学中西医结合学院(兰州市 730000)
- Keywords:
colorectal cancer(CRC);
fecal testing;
screening;
early diagnosis
- From:
Chinese Journal of Clinical Oncology
2024;51(16):852-856
- CountryChina
- Language:Chinese
-
Abstract:
In recent years,significant progress has been made in screening for and diagnosis of colorectal cancer(CRC),particularly using fecal nucleic acid detection.In addition to fecal occult blood tests,fecal screening technologies including fecal nucleic acid testing,multi-tar-get DNA testing,and protein biomarker detection,have become research hotspots.Numerous studies at home and abroad have identified various fecal nucleic acids and biomarkers with potential value for screening and early diagnosis of CRC.Fecal nucleic acid and biomarker testing can accurately detect early stage cancer and precancerous lesions,thereby improving early detection rates and reducing CRC incid-ence and mortality.This article reviews research progress into fecal nucleic acid testing in CRC screening,discusses the application prospects of biomarkers and optimization of detection techniques,and provides a basis for the development of more accurate and efficient screening methods.
