Correlation between ultrasound examination parameters and thromboelastogram in antithrombotic treatment for patients with atrial fibrillation
10.3969/j.issn.1672-8270.2024.10.016
- VernacularTitle:超声检查参数及血栓弹力图在房颤患者抗血栓药物治疗中的相关性
- Author:
Zhixin WANG
1
;
Yimin ZHONG
;
Tao LIU
Author Information
1. 武汉市红十字会医院心血管内科 武汉 430000
- Keywords:
Atrial fibrillation;
Antithrombotic drugs;
Ultrasound parameters;
Thrombologram
- From:
China Medical Equipment
2024;21(10):86-89
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the correlation between the use of antithrombotic drugs,results of ultrasound examination and the change characteristics of thromboelastogram in patients with atrial fibrillation.Methods:A total of 80 patients with atrial fibrillation who admitted to Wuhan Red Cross Hospital were selected from January 2021 to October 2022.According to with or without thrombosis in patients,they were divided into an observation group(with thrombosis,26 cases)and a control group(without thrombosis,64 cases).All patients were treated by using antithrombotic drugs.Both of two groups underwent ultrasound and thromboelastogram examinations before and after treatment.The difference of the examination results between the two groups were compared.The correlation analysis was adopted to analyze the correlation between each indicator and the curative effect of antithrombotic drugs in patients with atrial fibrillation.Results:There was no significant difference in examination indicators of echocardiogram between the two groups before treatment(P>0.05).After treatment,the left atrial ejection fraction and left ventricular ejection fraction of the observation group were significantly lower than those of the control group(t=5.325,5.285,P<0.05).The differences in the indicators of thromboelastogram between the two groups were not significant before treatment(t=1.325,1.425,P>0.05),respectively.After treatment,the response time(R value)[(5.0±1.6)min]and coagulation time(K value)[(2.4±0.6)min]of the observation group were significantly lower than(9.8±2.2)min and(5.7±1.8)min of the control group(t=5.326,5.564,P<0.05),and the differences were significant(t=5.362,5.564,P<0.05),respectively.The correlation analysis indicated that there were correlations between left atrial ejection fraction,left ventricular ejection fraction,R value,K value and the risks of anti-reducing thrombosis formation and the use effect of thrombotic drugs in patients with atrial fibrillation(r=0.552,0.546,0.546,0.532,P<0.05),respectively.Conclusion:The results of ultrasound examination and the change characteristics of thromboelastogram can guide patients with atrial fibrillation to use antithrombotic drugs,thereby increase the benefit rate of antithrombotic treatment,and improve the prognosis of patients.
