Assessment of axillary lymph node metastasis in breast cancer by multimodal MRI
10.3969/j.issn.1672-8270.2024.05.012
- VernacularTitle:多模态磁共振成像评估乳腺癌腋窝淋巴结转移
- Author:
Jing XU
1
;
Guanghui MA
;
Penghua LIU
Author Information
1. 邯郸市第一医院CT室 邯郸 056002
- Keywords:
Multimodal magnetic resonance imaging(MRI);
Breast cancer;
Axillary lymph node metastasis(ALNM);
Dynamic contrast enhanced-magnetic resonance imaging(DCE-MRI)
- From:
China Medical Equipment
2024;21(5):64-68
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the assessment effect and reliable indicators of multimodal magnetic resonance imaging(MRI)for axillary lymph node metastasis(ALNM)of breast cancer.Methods:A total of 152 female patients with breast cancer who were diagnosed and received surgical treatment in Handan First Hospital from January 2020 to November 2021 were selected.According to the pathological results of postoperative axillary lymph node,45 cases with ALNM were selected as ALNM group,and 107 cases without ALNM were selected as non-ALNM group.Dynamic contrast enhanced-magnetic resonance imaging(DCE-MRI),T2weighted image(T2WI)and diffusion-weighted imaging(DWI)were used to determine breast cancer ALNM.Results:The diagnostic sensitivity,specificity,positive predictive value and negative predictive value and diagnostic consistent rate of multimodal MRI were respectively 82.22%,96.26%,90.24%,92.79%and 92.11%.Logistic regression analysis showed that the maximum tumor size and ADC value were closely correlated with lymph node metastasis.The receiver operating characteristic(ROC)curve analysis showed that the area under curve(AUC)of the maximum tumor diameter was 0.797(95%CI=0.694～0.842,P<0.01),and the diagnostic sensitivity and specificity were respectively 77.4%and 60.7%when the optimal cut-off value was 1.96cm.The AUC of ADC value was 0.844(95%CI=0.808-0.915,P<0.01),and the diagnostic sensitivity and specificity were respectively 82.1%and 71.2%when the optimal cutoff value was 1.122×10-3mm2/s.The AUC value of the combined diagnosis of maximum tumor diameter and AUC value was 0.952(95%CI:0.904-0.991,P<0.01),and the sensitivity and specificity were respectively 88.6%and 81.4%under the optimal cutoff value.The AUC value of the combined indicators was higher than that of the maximum tumor diameter(Z=3.982,P<0.05)and ADC value(Z=3.014,P<0.05),respectively.Conclusion:Multimodal MRI has a good diagnostic effect on breast cancer ALNM,in which the maximum tumor diameter and AUC value are important reference indicators,and the combination of them can improve the diagnostic efficiency.
