Development and validation of a novel cerebral oximeter using near-infrared spectroscopy
10.3969/j.issn.1005-202X.2024.07.014
- VernacularTitle:基于近红外光谱的脑组织氧监测系统研发与验证
- Author:
Shijie CAI
1
;
Hanlin LI
;
Zhao SHEN
;
Hui YU
;
Jilun YE
;
Xu ZHANG
Author Information
1. 深圳市生物医学工程重点实验室,广东深圳 518060;深圳大学医学部生物医学工程学院,广东深圳 518060
- Keywords:
regional cerebral oxygen saturation;
arterial blood oxygen saturation;
near-infrared spectroscopy;
spatially resolved spectroscopy;
controlled hypoxia experiment
- From:
Chinese Journal of Medical Physics
2024;41(7):876-882
- CountryChina
- Language:Chinese
-
Abstract:
A cerebral oximeter based on 3-wavelength spatially resolved spectroscopy and the modified Lambert-Beer law is proposed.A platform for monitoring the regional cerebral oxygen saturation(rSO2)is established,and the system reliability is verified through spectral stability and background noise test.Eighteen volunteers are recruited to participate in the controlled hypoxia test for exploring the trend of rSO2 with the sequence of stepped hypoxia platform and discussing the relationship between rSO2 and arterial blood oxygen saturation.The results show that the established system can effectively monitor rSO2 and meet the measurement requirements.During the controlled hypoxia sequence,as the fraction of inspired oxygen decreases,rSO2 shows a downward trend,and the individual rSO2 has a high correlation with arterial blood oxygen saturation.
