Research progress of recanalization after ineffective endovascular therapy in acute large vascular occlusive ischemic stroke
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn431274-20231118-00569
   		
        
        	
        		- VernacularTitle:急性大血管闭塞性缺血性卒中血管内治疗无效再通的研究进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Zhoujingni YANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Zhihong ZHAO
			        		
			        		;
		        		
		        		
		        		
			        		Jianjun ZOU
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 湖南省人民医院(湖南师范大学附属第一医院)神经内科,长沙 410005
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Acute ischemic stroke;
			        		
			        		
			        		
				        		Endovascular treatment;
			        		
			        		
			        		
				        		Futile recanalization
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Chinese Physician
	            		
	            		 2024;26(11):1743-1747
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	Acute ischemic stroke is a major disease threatening the life and health of middle-aged and elderly people, and intravascular therapy is the most rapid and effective treatment for acute ischemic stroke. However, clinical findings showed that patients who were often treated intravascular within the time window or beyond the time window could not achieve functional independence for 90 days after vascular recanalization, that is, ineffective recanalization. Ineffective recanalization seriously affects the efficacy of intravascular therapy and has become the focus of clinical research by neurologists. In this paper, the mechanism and influencing factors of ineffective recanalization in acute large vascular occlusive ischemic stroke in recent years, as well as possible ways to reduce its occurrence, are comprehensively reviewed, providing references for clinicians to develop more reasonable and perfect programs.