Retrospective study on 159 cases of malignant tumors of the digestive tract with ovarian metastasis
10.3760/cma.j.cn431274-20231101-00493
- VernacularTitle:消化道恶性肿瘤卵巢转移159例的回顾性研究
- Author:
Fei BAI
1
;
Ke LI
;
Peng LIU
;
Fang XIANG
Author Information
1. 湖南省肿瘤医院 中南大学湘雅医学院附属肿瘤医院胃十二指肠胰腺外科，长沙 410013
- Keywords:
Gastrointestinal neoplasms;
Ovarian neoplasms;
Neoplasm metastasis
- From:
Journal of Chinese Physician
2024;26(9):1374-1378
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of different treatment methods on the survival time of patients with ovarian metastasis of digestive tract malignant tumors.Methods:A retrospective analysis was conducted on the clinical data of 159 patients with gastrointestinal malignant tumors and ovarian metastases admitted to Hunan Cancer Hospital from 2008 to 2018. They were divided into 5 groups according to different treatment methods. Group A (94 cases): Total resection of primary and metastatic lesions+ chemotherapy; Group B (13 cases): Primary lesion resection+ chemotherapy; Group C (12 cases): Only metastatic lesions were removed; Group D (17 cases): Resection of metastatic lesions+ chemotherapy; Group E (23 cases): Both the primary and metastatic lesions were not removed, and chemotherapy was used alone. A survival curve was plotted using R language and Kaplan Meier method, and the impact of different treatment methods on patient survival time was analyzed.Results:Among the 159 patients, the average survival time of patients in groups A, B, C, D, and E was 26.6, 23, 17.3, 20.3, and 16 months, respectively. Compared with groups E, C+ D, and B, the survival time of the group A was extended by 10.6( P=0.018), 9.3( P=0.013), and 3.3( P=0.003 1)months, respectively, while there was no statistically significant difference between the other groups (all P>0.05). Conclusions:Patients who undergo surgery to simultaneously remove both primary and metastatic lesions and receive chemotherapy have significantly longer survival times, while patients who only remove metastatic lesions and receive chemotherapy have slightly longer survival times. Not undergoing surgery or only removing metastatic lesions or primary lesions does not help prolong patient survival times.
