Progress and prospects in the diagnosis and treatment of gastrointestinal stromal tumors
10.3760/cma.j.cn431274-20240711-01077
- VernacularTitle:胃肠间质瘤的诊治进展和展望
- Author:
Zaiyuan YE
1
;
Xiao ZHANG
Author Information
1. 浙江省人民医院（杭州医学院附属人民医院）普通外科胃肠胰外科，杭州 310014
- Keywords:
Gastrointestinal stromal tumors;
Laparoscopy
- From:
Journal of Chinese Physician
2024;26(8):1121-1128
- CountryChina
- Language:Chinese
-
Abstract:
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor originating from the gastrointestinal tract, mainly associated with KIT and PDGFRA gene mutations, and related to factors such as patient age, gender, and pathological differentiation level. The clinical manifestations of GIST include abdominal pain, indigestion, gastrointestinal bleeding, etc. The diagnostic methods involve endoscopy, imaging examination, and pathological evaluation. The treatment strategy for GIST is customized based on tumor characteristics and individual circumstances, including surgery, drug therapy, and targeted therapy. With the development of molecular biology, the understanding of GIST has become increasingly profound, and various diagnostic techniques and treatments for GIST have made new progress, especially in individualization, precision medicine, and targeted therapy.
