Treatment strategies based on the etiology transformation and functional status adjustment of portal hypertension
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn431274-20240326-00510
   		
        
        	
        		- VernacularTitle:基于门静脉高压病因转变与功能状态调整治疗策略
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Xiaoquan HUANG
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Shiyao CHEN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 复旦大学附属中山医院消化科,上海 200032
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Hypertension, portal;
			        		
			        		
			        		
				        		Esophageal and gastric varices;
			        		
			        		
			        		
				        		Endoscopy
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Journal of Chinese Physician
	            		
	            		 2024;26(4):481-483
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
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		        	Abstract:
			       	
			       		
				        
				        	In recent years, the etiology of portal hypertension has undergone many changes. In addition to the focus on viral and alcoholic liver diseases, obesity, hyperlipidemia and diabetes patients, all kinds of drugs, especially after chemotherapy with platinum drugs, bone marrow proliferative diseases, autoimmune liver disease patients, need to be included in the high-risk screening population. The change in etiology brings about complex pathological and physiological states. We need to conduct a comprehensive evaluation, understand past medical history, improve portal vein computed tomography (CT), liver elastography, gastroscopy and other examinations, clarify the etiology, and choose personalized treatment plans for patients. Through technological innovation, we aim to improve the efficacy of endoscopic therapy, combined with new concepts such as artificial intelligence, big data, and multi omics, so as to obtain more accurate prediction of portal vein pressure and clinical characteristics, refine risk stratification, and make more accurate personalized decisions for clinical diagnosis and treatment.