Status quo and prospects of toxicological data quality evaluation
10.3867/j.issn.1000-3002.2024.10.009
- VernacularTitle:毒理学数据质量评价现状与展望
- Author:
Min LING
1
;
Qian BIAN
Author Information
1. 江苏省疾病预防控制中心毒理与风险评估研究所,江苏南京 210009
- Keywords:
quality of toxicological data;
alternative methods;
data quality evaluation system;
risk assessment
- From:
Chinese Journal of Pharmacology and Toxicology
2024;38(10):787-795
- CountryChina
- Language:Chinese
-
Abstract:
The quality of toxicological data is critical to toxicity assessment and risk prediction.Inte-grating multiple streams of evidence and enhancing the quality of toxicological data are indispensable for more efficient and precise health risk assessment.There are several commonly used toxicology data quality evaluation systems abroad,which include Klimisch rating system,ToxRTool evaluation tool,the SciRAP evaluation tool and the integrated risk information system tool.The TRAM reliability evaluation tool is developed in China for toxicology data in food safety risk assessment.These evaluation tools have different backgrounds and applicability of evaluation standards.Each evaluation system also has its advantages and disadvantages.
