Diagnostic efficiency evaluation of isolated-check visual evoked potential on primary open-angle glaucoma
10.12007/j.issn.0258-4646.2024.10.011
- VernacularTitle:视觉诱发电位分离格栅模式对原发性开角型青光眼的诊断效能分析
- Author:
Qiao YU
1
;
Xin LIU
;
Qian HU
;
Wanning LIU
;
Bo QU
Author Information
1. 中国医科大学附属第四医院眼科,中国医科大学眼科医院,辽宁省晶状体学重点实验室,沈阳 110005;贵州省人民医院眼科,贵阳 550000
- Keywords:
isolated-check visual evoked potential;
primary open-angle glaucoma;
diagnostic efficiency
- From:
Journal of China Medical University
2024;53(10):934-938
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the accuracy,sensitivity,and specificity of isolated-check visual evoked potential(Ic-VEP)in the diagnosis of primary open-angle glaucoma(POAG).Methods The participants were 52 patients(104 eyes)with POAG and 40 healthy controls(80 eyes).All participants were examined using Ic-VEP and Humphrey perimetry to record the signal-to-noise ratio and mean devia-tion.Receiver operating characteristic(ROC)curve analysis was used to characterize the diagnostic performance of Ic-VEP in POAG.Results The sensitivity,specificity,and accuracy of the Ic-VEP qualitative examination were 92.3％,80.0％,and 88.0％,respectively.The area under the curve(AUC)was 0.873(95％CI:0.793-0.953).The sensitivity,specificity,and accuracy of the Ic-VEP quantitative examination were 91.3％,81.3％,and 87.0％,respectively.The AUC was 0.863(95％CI:0.804-0.922).The sensitivity of Ic-VEP in the early stage of POAG(81.3％)was slightly lower than that in the middle and late stages(82.0％),but the difference was not statisti-cally significant(x 2=0.001,P=0.981).The sensitivity of Ic-VEP quantitative examination in the early stage of POAG(88.4％)was slightly lower than that in the middle and late stages(93.4％);however,the difference was not statistically significant(x2=0.037,P=0.847).Conclusion Ic-VEP is an effective diagnostic instrument for middle-late and early stages of POAG.
