Application of extracorporeal membrane oxygenation combined with renal replacement therapy in the treatment of war traumatic sepsis
10.3760/cma.j.cn121430-20231209-01072
- VernacularTitle:体外膜肺氧合联合肾脏替代治疗在战创伤后脓毒症救治中的应用
- Author:
Liwen HU
1
;
Yi SHEN
Author Information
1. 中国人民解放军东部战区总医院心胸外科，江苏南京 210002
- Keywords:
Sepsis;
Shock;
Extracorporeal membrane oxygenation;
Renal impairment;
Renal replacement therapy
- From:
Chinese Critical Care Medicine
2024;36(9):1005-1008
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is an important factor for trauma related death, especially the refractory septic shock, which has a mortality rate exceeding 50%. The treatment of sepsis is a medical problem that needs to be solved urgently. The role and status of extracorporeal membrane oxygenation (ECMO) in the treatment of cardiopulmonary failure has become more and more prominent, and its role in the treatment of sepsis in children and infants has gained remarkable achievements. However, its role in adult sepsis remains controversial, with current reports showing varied outcomes for ECMO in adult sepsis treatment. ECMO application can potentially cause renal impairment, and renal impairment can affect the outcomes of ECMO treatment in turn. Studies have shown that adjunctive renal replacement therapy during non-ECMO treatment of septic shock can improve the prognosis, and whether the combination with renal replacement therapy in the early stage of ECMO treatment can effectively improve the treatment outcome still needs to be confirmed by multicenter and prospective studies. Based on this, this article reviews the relevant research on the application of ECMO combined with renal replacement therapy in the treatment of sepsis after war trauma, aiming to provide clinical reference for the treatment of sepsis after war trauma.
