The value of plasma biological indicators in predicting type 2 diabetes mellitus patients combined with metabolic associated fatty liver disease
10.3969/j.issn.1006-6187.2024.09.007
- VernacularTitle:2型糖尿病合并代谢相关脂肪性肝病血浆预测标志物的研究
- Author:
Haiyan LIN
1
;
Jun ZHU
;
Xiang LIU
;
Xingjin ZHANG
;
Shandong YE
Author Information
1. 243000 德驭医疗马鞍山总医院内分泌科
- Keywords:
Diabetes mellitus,type 2;
Metabolic associated fatty liver disease;
Atherogenic index of plasma
- From:
Chinese Journal of Diabetes
2024;32(9):671-674
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the value of atherogenic index of plasma(AIP),peripheral bloodmonocyte/high-density lipoprotein cholesterolratio(MHR)and serum uricacid/high-densitylipoprotein cholesterol ratio(UHR)in predicting metabolic associated fatty liver disease(MAFLD)in patients with type 2 diabetes mellitus(T2DM).Methods 156 T2DM patients who were treated in Maanshan General Hospital of Ranger-Duree Healthcare from November 2021 to August 2022 were selected and divided into simple T2DM group(n=67)and T2DM combined with MAFLD group(T2DM+MAFLD,n=89)based on liver color ultrasound examination.Results Compared with T2DM group,BMI,WHR,FPG,HbA1c,TG,AIP,MHR and UHR were higher in T2DM+MAFLD group,while the level of HDL-C was lower(P<0.05).Pearson correlation analysis showed that AIP was positively correlated with BMI,WHR,FPG,HbA1c and LDL-C(P<0.05).Logistic regression analysis showed that BMI and AIP were the influencing factors of T2DM combined with MAFLD.The analysis of the working characteristic curve of the subjects showed that the area under the curve of BMI and AIP in predicting for T2DM combined with MAFLD were 0.702 and 0.680,with sensitivity of 68.5%and 59.6%,specificity of 68.7%and 71.6%respectively.Conclusions BMI and AIP are associated with T2DM combined with MAFLD,and can be used as clinical predictive markers.
