Research Progress on Invasive Fungal Infection after Allogeneic Hematopoietic Stem Cell Transplantation——Review

VernacularTitle:异基因造血干细胞移植术后侵袭性真菌感染的最新研究进展
Author: Zhong-Yu LI ¹ ; Yan-Ping WU ; Xue BAI ; Jia-Jia LI
Author Information

1. 蚌埠医科大学第一附属医院血液科,安徽蚌埠233000
Keywords: allogeneic hematopoietic stem cell transplantation; invasive fungal infection; aetiology; diagnosis; treatment
From: Journal of Experimental Hematology 2024;32(6):1937-1940
CountryChina
Language:Chinese
Abstract: Allogeneic hematopoietic stem cell transplantation (allo-HSCT)is one of the main treatment methods for hematological malignancies.With the continuous improvement and popularization of transplantation technology,it has brought hope for prolonging the lives and improving the survival rate of patients with hematological malignancies. However,postoperative invasive fungal infection (IFI)is the most common infectious complication and the main cause of death,with difficult early diagnosis and extremely high mortality.This paper summarizes the latest research progress on the pathogenic types,diagnostic methods,high-risk factors and treatment regimen of Candida,Aspergillus and Mucor associated with postoperative IFI,which is expected to provide references for improving the early diagnosis rate and treatment effectiveness of postoperative IFI.