Current Status of Application and Quality Evaluation of Commer-cial Platelet Pathogen Reduction Technology——Review
10.19746/j.cnki.issn1009-2137.2024.04.050
- VernacularTitle:商品化血小板病原体灭活技术的应用现状及质量评价
- Author:
Bin FAN
1
;
Chun-Hui YANG
;
Bin LI
;
Li-Min CHEN
Author Information
1. 中国医学科学院、北京协和医学院输血研究所输血传播传染病省级重点实验室,四川成都 610062
- Keywords:
blood transfusion;
pathogen inactivation;
platelet transfusion
- From:
Journal of Experimental Hematology
2024;32(4):1300-1304
- CountryChina
- Language:Chinese
-
Abstract:
With the development of transfusion medicine,platelet pathogen contamination is of increasing concern to the industry.Currently,pathogen reduction technology(PRT)has been successfully applied to platelets and achieved good results.This paper provides an overview of the research progress of commercial platelet PRT,a comprehensive analysis of the current application status of platelet PRT,preclinical mechanism studies,clinical cohort studies and alternative or complementary strategies,and makes recommendations to provide a scientific basis for safeguarding blood safety in China and developing platelet PRT products applicable to our national conditions.
