Epidemiological and clinical characteristics of 44 cases of mpox in the Changsha City
10.3969/j.issn.1002-2694.2024.00.136
- VernacularTitle:长沙市44例猴痘病例流行病学及临床特征
- Author:
Quan ZHOU
1
;
Xue-Feng YUAN
;
Gang XIAO
Author Information
1. 中南大学湘雅医学院附属长沙医院医院感染管理部,长沙 410000;中南大学湘雅医学院附属长沙医院感染科,长沙 410000
- Keywords:
mpox;
HIV;
epidemiology;
MSM;
rash
- From:
Chinese Journal of Zoonoses
2024;40(9):893-897
- CountryChina
- Language:Chinese
-
Abstract:
This study investigated the clinical and epidemiological characteristics of patients with monkeypox in the Chang-sha City,and analyzed the results of laboratory and ultrasound examinations,to provide a basis for monkeypox epidemic pre-vention and control.Epidemiological characteristics,clinical manifestations,laboratory tests,and ultrasound examinations for 44 patients with monkeypox hospitalized at the First Hospital of Changsha between June 29,2023,and December 15,2023,were analyzed.Differences in laboratory results were compared between patients with monkeypox with versus without HIV in-fection.The median age of the 44 patients with monkeypox was 33 years.All patients were men who had sex with men within 21 days before the diagnosis of monkeypox.A total of 81.82％patients were unmarried,and 38.64％were unemployed.Moreo-ver,40.91％of patients were infected with Treponema pallidum,and 61.36％patients were infected with HIV,of whom 88.89％received ART.The median incubation period was 5 days.The median time from onset to hospitalization was 6.88 days.The median hospitalization time was 10.51 days.All patients presented with skin rash,distributed primarily in the repro-ductive organs,limbs,facial features,trunk,and perianal area.Most patients had fever.Lymph node enlargement oc-curred mainly in the groin.Compared with patients who were co-infected with HIV,the other patients had lower levels of neutrophils,and higher levels of red blood cells,albumin,aspartate aminotransferase,total bilirubin,and creatine kinase isoenzymes.Most patients with monkeypox in the Changsha City were middle-aged or young men who had sex with men.The main manifestations included rash,fever,and enlarged lymph nodes.
