Temperature sensitivity of respiratory viruses during viral infection
10.3969/j.issn.1002-2694.2024.00.077
- VernacularTitle:呼吸道病毒在感染过程中对温度的敏感性
- Author:
Xi-Li FENG
1
;
Ming-Yang GAO
;
Yu-Hu WU
;
Xuan-Ye YANG
;
Xiao-Xia MA
Author Information
1. 西北民族大学,生物医学研究中心,生物工程与技术国家民委重点实验室,兰州 730030;西北民族大学,生物医学研究中心,甘肃省动物细胞技术创新中心,兰州 730030;西北民族大学,生命科学与工程学院,兰州 730030
- Keywords:
respiratory virus;
temperature sensitivity;
infection;
virus replication;
innate immunity
- From:
Chinese Journal of Zoonoses
2024;40(6):564-570
- CountryChina
- Language:Chinese
-
Abstract:
Because of the special structural features of the respiratory system,respiratory viruses experience temperature changes during passage through the upper airways.The infection and replication dynamics of respiratory viruses is influenced by the different upper airway temperatures.Respiratory viruses possess evolutionary adaptations to cope with different tempera-tures in the upper airways.The temperature sensitivity of some respiratory viruses limits their spread in the respiratory system.However,the antiviral activity from the immune response in the upper airways varies under different temperatures,thus enab-ling new viral shelter pathways.This review includes a discussion of the effects of temperature on viral replication dynamics,the stability of virion offspring,viral infectivity,and the innate immune response.
