Research progress on mitochondrial transfer in the pathogenesis of ischemic stroke
10.3969/j.issn.1672-5921.2024.05.007
- VernacularTitle:线粒体转移在缺血性卒中中的研究进展
- Author:
Yuzheng HUANG
1
;
Yanling YIN
Author Information
1. 100069 北京,首都医科大学基础医学院神经生物学系
- Keywords:
Ischemic stroke;
Mitochondrial transfer;
Tunneling nanotubes;
Extracellular vesicles;
Gap junction;
Review
- From:
Chinese Journal of Cerebrovascular Diseases
2024;21(5):333-340
- CountryChina
- Language:Chinese
-
Abstract:
The epidemiology of ischemic stroke is characterized by a high incidence,high mortality and disability rates,and a high recurrence rate,yet current clinical treatment methods are limited.The onset of ischemic stroke is closely related to mitochondrial transfer.Mitochondria plays a crucial role in cellular energy supply,signal transmission,and other functions.In recent years,research on the application of mitochondrial transfer in the treatment of ischemic stroke has made progress.The authors reviewed the current research progress on mitochondrial transfer following ischemic stroke,aiming to highlight the existing research gaps and future prospects.This review provides guidance for the development of new clinical treatment methods for ischemic stroke.
