Identification of undifferentiated and differentiated gastric cancer under endoscope based on Kyoto classification score
- VernacularTitle:京都胃炎分类评分在胃镜下识别未分化型与分化型胃癌的价值
- Author:
Chao LI
1
;
Lihong CUI
;
Xiaohui WANG
;
Lan YU
;
Wei WANG
;
Xinyao LIU
;
Xiaowei LI
;
Zhihui YAN
Author Information
- Keywords: gastric cancer; endoscope; Kyoto classification; undifferentiated carcinoma
- From: China Journal of Endoscopy 2024;30(7):71-76
- CountryChina
- Language:Chinese
- Abstract: Objective To explore the value of the Kyoto classification score in differentiating undifferentiated gastric cancer from differentiated gastric cancer,and establish a predictive scoring system for differentiating undifferentiated gastric cancer under endoscope.Methods 183 gastric cancer patients were retrospectively analyzed.According to pathology,95 patients were included in the differentiated group and 88 were included in the undifferentiated group.The age,gender and Kyoto classification score of patients in the two groups were compared,and the factors associated with undifferentiated gastric cancer were screened by binary Logistic regression analysis.The predictive scoring system for undifferentiated gastric cancer was established based on the obtained odds ratio(O(R))values,and the receiver operator characteristic curve(ROC curve)was drawn.Results Compared with differentiated group,the total scores of Kyoto classification,atrophy,intestinal metaplasia and diffuse redness were lower in undifferentiated group(P<0.01).Under the age of 55(P<0.05),female(P<0.05),and C1 atrophy or no atrophy(P<0.01)were independently associated with undifferentiated gastric cancer.The area under the curve(AUC)of predictive scoring system for undifferentiated gastric cancer was 0.881(95％CI:0.828～0.934),and the sensitivity and specificity were 80.70％and 90.50％at the optimal cut-off value.Conclusion There are differences in Kyoto classification scores between undifferentiated and differentiated gastric cancer patients.The predictive scoring system of undifferentiated gastric cancer established by us has certain value in distinguishing undifferentiated gastric cancer under endoscope.
