Pathological mechanism of acute attack and spontaneous resolution of gouty arthritis
10.3969/j.issn.1000-484X.2024.11.037
- VernacularTitle:痛风性关节炎急性发作及自发性消退的病理机制研究
- Author:
Suhong SHENG
1
;
Zhenmin LUO
;
Chuangchuang MENG
;
Kehui ZHANG
Author Information
1. 绍兴市中医院风湿科,绍兴 312000
- Keywords:
Gouty arthritis;
Acute attacks;
Spontaneous regression;
Pathological mechanisms;
Treatment strategies
- From:
Chinese Journal of Immunology
2024;40(11):2458-2464
- CountryChina
- Language:Chinese
-
Abstract:
The prevalence of gouty arthritis is increasing year by year.Acute attacks seriously affect work and life.Poor control of chronic recurrent attacks may lead to teratogenicity and disability.Targeted reduction of serum uric acid levels and crystallolysis is the key to gout treatment.Although its treatment guidelines are relatively complete and drug choices are relatively wide,the clinical effect is still not satisfactory.This review focuses on the molecular and cytopathological mechanisms behind the clinical manifestations of acute attack and spontaneous remission of gouty arthritis,so as to further understand the necessity of standardized clinical medica-tion and explore its potential treatment strategies.
