Research progress on immunomodulatory effects of short chain fatty acids in food allergy
10.3969/j.issn.1000-484X.2024.07.035
- VernacularTitle:短链脂肪酸在食物过敏中的免疫调节作用研究进展
- Author:
Yonglu YU
1
;
Hai XIE
;
Lingzhi XU
Author Information
1. 山东第二医科大学基础医学院,山东省高等学校免疫微环境与炎症性疾病研究特色实验室,潍坊 261053
- Keywords:
Short chain fatty acids;
Food allergy;
Intestinal epithelium cell;
Immune cells;
Immunomodulatory effects
- From:
Chinese Journal of Immunology
2024;40(7):1553-1558
- CountryChina
- Language:Chinese
-
Abstract:
Food allergy(FA)is a pathological and potentially fatal immune response,whose incidence continues to rise and has become an important public health problem affecting children and adults.Short chain fatty acids(SCFAs),produced by bacteria,through the fermentation of dietary fibre in the gut,played an important role in in pathogenesis of FA.In this review,we will discuss the immunomodulatory effects of SCFAs on the intestinal epithelial cells and various immune cells and their related molecular mecha-nisms in the context of FA,providing new perspectives for the prevention and treatment of FA.
