The assessment of abnormal brain function in patients with mild cognitive impairment based on fNIRS brain imaging

VernacularTitle:基于近红外脑功能成像的老年轻度认知障碍患者脑功能异常评估
Author: Guodong XU ¹ ; Wenyu JIANG ; Jingsha ZHANG
Author Information

1. 江苏省丹阳市人民医院,江苏省丹阳市,212300
Keywords: mild cognitive impairment; functional near-infrared spectroscopy; hemodynamic response
From: Chinese Journal of Rehabilitation Medicine 2024;39(11):1606-1612,1643
CountryChina
Language:Chinese
Abstract: Objective:To establish the haemodynamic response during the verbal fluency task(VFT)in patients with MCI and to find a screening tool that could be used as a predictor of dementia. Method:Functional near-infrared spectroscopy(fNIRS)can detect changes in blood oxygen in the brain,thus revealing the patient's functional brain activity status,and is used to study the level of brain function in MCI.We evaluated the hemodynamic response in the prefrontal and temporal regions of MCI patients and healthy controls in our study. Result:The results found a significantly reduced haemodynamic response in the prefrontal brain regions in the MCI group. Conclusion:The results suggested that a reduced haemodynamic response in the prefrontal brain regions could be used as a diagnostic biomarker for dementia.