Quantitative CT for assessing complications of type 2 diabetes mellitus
10.13929/j.issn.1672-8475.2024.11.011
- VernacularTitle:定量CT评估2型糖尿病并发症
- Author:
Xiaojun CHEN
1
;
Jin LIU
;
Xiaoling LIANG
;
Jun GONG
;
Shaolin LI
Author Information
1. 中山大学附属第五医院放射科,广东 珠海 519000
- Keywords:
diabetes mellitus,type 2;
diabetes complications;
bone density;
tomography,X-ray computed;
fat quantification
- From:
Chinese Journal of Interventional Imaging and Therapy
2024;21(11):702-707
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of quantitative CT(QCT)for assessing complications of type 2 diabetes mellitus(T2DM).Methods Totally 220 T2DM patients were included and divided into uncomplicated group(n=40),mono-complicated group(n=84)and multi-complicated group(n=96).Bone mineral density(BMD)of L2—L4,as well as visceral adipose tissue(VAT)and subcutaneous adipose tissue(SAT)area were collected using QCT and compared among groups.The operator characteristic curves were drawn,and the area under the curves(AUC)were calculated to observe the value of QCT indicators and comprehensive model based on clinical indicators and QCT indicators for evaluating complications of T2DM.Decision curve analysis(DCA)and clinical impact curve(CIC)analysis were used to analyze the clinical application value of the comprehensive model.Results Significant differences of patients’age,lumbar BMDs and areas of VAT were found among 3 groups(all P＜0.05).The AUC of comprehensive model for differentiating uncomplicated group from mono-complicated group,uncomplicated group from multi-complicated group and mono-complicated group from multi-complicated group was 0.753,0.865,and 0.761,respectively,higher than that of BMD,VAT and SAT area(all P＜0.05).DCA and CIC analyses showed that comprehensive model yielded clinical benefits and had good clinical applicability for assessing complications of T2DM.Conclusion QCT was valuable for assessing complications of T2DM.
