Summary of best evidence for management of acute kidney injury after liver transplantation
10.3760/cma.j.cn115682-20220923-04707
- VernacularTitle:肝移植患者术后急性肾损伤管理的最佳证据总结
- Author:
Qiuying XU
1
Author Information
1. 首都医科大学附属北京友谊医院重症医学科，北京 100050
- Keywords:
Liver transplantation;
Acute kidney injury;
Evidence summary;
Evidence-based nursing
- From:
Chinese Journal of Modern Nursing
2023;29(24):3290-3295
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the best evidence for the management of acute kidney injury (AKI) after liver transplantation, so as to provide evidence-based basis for preventing the occurrence of AKI and improving the prognosis of patients after liver transplantation.Methods:Using Population, intervention, professional, outcome, setting and type of evidence (PIPOST) to establish evidence-based questions, all evidence on postoperative AKI in liver transplant patients is systematically searched on UpToDate, British Medical Journal (BMJ) Best Practice, Cochrane Library, National Guideline Clearinghouse, National Institute for Health and Clinical Excellence, Scottish Intercollegiate Guidelines Network, Joanna Briggs Institute Evidence-Based Health Care Center Database, China Biomedical Literature Database, China National Knowledge Infrastructure, WanFang Data and so on. Article types included clinical guidelines, expert consensus, evidence summary, systematic review, best practice information handbook and randomized controlled trial. The search period was from database establishment to September 30, 2022. The relevant evidence was summarized and evaluated.Results:A total of 11 articles were included, involving one guideline, five expert consensus, three systematic reviews, one randomized controlled trial, and one quasi experimental study. Finally, a total of 16 best pieces of evidence were summarized from four aspects, including incidence, risk factors, renal function protection plan, and impact on prognosis.Conclusions:This study summarizes the evidence of postoperative AKI management in liver transplant patients, which can provide evidence-based basis for clinical healthcare professionals. As the evidence in this study comes from both domestic and foreign sources, personalized and targeted plans should be developed based on the patient's situation when applying evidence, in order to reduce the risk of AKI and improve the patient's quality of life.
