Factors influencing vascular crisis in free tissue flap repair for oral and maxillofacial defects after tumor surgery: a Meta-analysis
10.3760/cma.j.cn115682-20220714-03425
- VernacularTitle:游离组织瓣修复口腔颌面部肿瘤术后缺损血管危象影响因素的Meta分析
- Author:
Ying ZHENG
1
;
Lu BAI
;
Xiaoqin BI
Author Information
1. 四川大学华西护理学院/四川大学华西口腔医院头颈肿瘤外科，成都 610041
- Keywords:
Neoplasms;
Oral maxillofacial region;
Free tissue flaps;
Vascular crisis;
Influencing factors;
Meta-analysis
- From:
Chinese Journal of Modern Nursing
2023;29(20):2708-2715
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the influencing factors of vascular crisis in the free tissue flap repair for oral and maxillofacial defects after tumor surgery through Meta-analysis.Methods:The articles on factors related to vascular crisis in the free tissue flap repair for oral and maxillofacial defects after tumor surgery were searched in Medline, Embase, the Cochrane Central Register of Controlled Trials, ProQuest, China National Knowledge Infrastructure, WanFang Data, VIP, and China Biology Medline disc. The search period was from the establishment of the database to August 31, 2022. Meta-analysis was conducted on the included articles using RevMan 5.3 software.Results:A total of 22 articles were included, including 6 Chinese articles and 16 English articles. There were 19 cohort studies and 3 case control studies. A total of 18 569 flaps were included, of which 976 had vascular crises. Meta-analysis showed that the influencing factors of vascular crisis in the free tissue flap repair for oral and maxillofacial defects after tumor surgery included preoperative radiotherapy [ RR=1.45, 95% CI (1.20, 1.76) ], diabetes [ RR=2.15, 95% CI (1.40, 3.31) ], anastomosing vessels with stapler [ RR=0.25, 95% CI (0.16, 0.41) ], anastomosing two vessels [ RR=0.44, 95% CI (0.21, 0.90) ] . Conclusions:The risk factors of vascular crisis in patients with oral and maxillofacial tumor defects repaired by free tissue flaps were preoperative radiotherapy and diabetes, while the use of stapler and anastomosis of two vessels were protective factors. Medical and nursing staff can identify and intervene in the vascular crisis in the free tissue flap repair for oral and maxillofacial defects after tumor surgery as early as possible based on the influencing factors.
