Meta-analysis of risk factors for aspiration pneumonia in elderly patients
10.3760/cma.j.cn115682-20220701-03187
- VernacularTitle:老年患者吸入性肺炎危险因素的Meta分析
- Author:
Xueli GAO
1
;
Xue LIU
;
Yanling WANG
;
Qian XIAO
Author Information
1. 首都医科大学护理学院，北京 100069
- Keywords:
Aged;
Pneumonia, aspiration;
Risk Factors;
Meta-analysis;
Evidence-based nursing
- From:
Chinese Journal of Modern Nursing
2023;29(8):1009-1016
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To systematically evaluate the risk factors of aspiration pneumonia (AP) in elderly patients, so as to provide evidence-based basis for clinical early prevention of AP.Methods:We systematically searched Chinese and English databases such as China National Knowledge Infrastructure (CNKI) , WanFang Data, VIP, China Biomedical Literature Database, Cochrane Library, PubMed, Web of Science, Embase. The search time limit was from the establishment of the database to December 31, 2021. After quality evaluation, RevMan 5.4.1 software was used for Meta-analysis.Results:A total of 20 articles were included, including 25 related risk factors. Meta-analysis results showed that the elderly [ MD=3.71, 95% CI (2.34, 5.09) , P<0.01], male [ OR=1.38, 95% CI (1.03, 1.58) , P<0.01], chronic underlying disease [ OR=0.13, 95% CI (0.04, 0.23) , P<0.01], Parkinson's disease [ OR=13.45, 95% CI (1.22, 148.88) , P<0.05], gastroesophageal reflux [ OR=2.47, 95% CI (2.03, 3.00) , P<0.01], history of aspiration [ OR=22.77, 95% CI (3.95, 31.36) , P<0.01], hypoalbuminemia [ OR=6.44, 95% CI (3.55, 11.66) , P<0.01], dysphagia [ OR=2.40, 95% CI (1.48, 3.88) , P<0.01], disorder of consciousness [ OR=3.39, 95% CI (2.18, 5.27) , P<0.01], cough disorder [ OR=9.62, 95% CI (2.84, 32.60) , P<0.01], cognitive disorder [ OR=3.50, 95% CI (1.06, 11.51) , P<0.05], use of sedatives [ OR=3.46, 95% CI (2.26, 5.30) , P<0.01], use of acid suppressants [ OR=3.42, 95% CI (1.32, 8.84) , P<0.05], nasal feeding [ OR=2.02, 95% CI (1.41, 2.89) , P<0.01], sputum aspiration [ OR=3.01, 95% CI (2.54, 3.57) , P<0.01], long-term bed rest [ OR=5.17, 95% CI (3.39, 7.87) , P<0.01], and improper posture [ OR=2.99, 95% CI (1.48, 6.05) , P<0.01] were risk factors for AP in elderly patients. Conclusions:AP in elderly patients is not the result of a single factor, but the result of a combination of individual factors, disease-related factors, treatment-related factors and other factors.
