Research progress on the role of CC and CXC chemokines in regulating di-fferent immune cells during influenza virus infection
10.12138/j.issn.1671-9638.20243459
- VernacularTitle:CC及CXC趋化因子在流感病毒感染过程中调控不同免疫细胞的作用研究进展
- Author:
Wen-Jing WANG
1
;
Shan-Yu ZHANG
;
Xiao-Long WANG
Author Information
1. 山东中医药大学药学院,山东 济南 250355;教育部中医药经典理论重点实验室,山东 济南 250355;山东省中医药基础研究重点实验室,山东 济南 250355
- Keywords:
influenza;
CC chemokine;
CXC chemokine;
chemokine receptor;
immune cell
- From:
Chinese Journal of Infection Control
2024;23(5):638-645
- CountryChina
- Language:Chinese
-
Abstract:
Influenza is an acute respiratory infectious disease caused by influenza virus infection.After influenza virus invades the human body through the respiratory tract,the epithelial cells of the respiratory tract react first and produce a variety of cytokines to induce immune responses of human body.CC chemokines and CXC chemokines regulate a variety of immune cells in the process of influenza virus infection,and play important roles in the control of inflammatory response and maintenance of homeostasis in human body at the early stage of influenza virus infec-tion.Analyzing the role of chemokines in regulating immune cells in host's body during the process of influenza vi-rus infection can provide new strategies for treating against influenza.In this paper,the regulatory effects on vari-ous types of immune cells by CC and CXC chemokines as well as their related receptors during influenza virus infec-tion are reviewed.
