Research progress of metabolomics in children with irritable bowel syndrome
10.7499/j.issn.1008-8830.2404130
- VernacularTitle:代谢组学在儿童肠易激综合征诊治中的研究进展
- Author:
Xiao-Long CHEN
1
;
Mi-Zu JIANG
Author Information
1. 浙江大学医学院附属儿童医院儿童内镜中心/国家儿童健康与疾病临床医学研究中心/国家儿童区域医疗中心,浙江杭州 310052;嘉善县第一人民医院儿科,浙江嘉兴 314100
- Keywords:
Irritable bowel syndrome;
Metabolomics;
Biomarker;
Metabolic pathway;
Child
- From:
Chinese Journal of Contemporary Pediatrics
2024;26(9):989-994
- CountryChina
- Language:Chinese
-
Abstract:
Irritable bowel syndrome(IBS)is a common functional gastrointestinal disorder characterized by symptoms such as abdominal pain,diarrhea,constipation,and indigestion.Given its unclear etiology and pathogenesis,and the absence of specific biomarkers,clinical diagnosis and treatment of IBS continue to pose significant challenges.In recent years,metabolomics technology,known for its non-invasive,high-throughput,high-precision,and highly reproducible features,has been widely applied in the diagnosis,treatment,and prognosis of various diseases.Therefore,metabolomics technology is expected to offer novel insights and methodologies for the biological mechanism research,diagnosis,and treatment of IBS.This article reviews recent advancements in the application of metabolomics to IBS,exploring its potential value in the clinical diagnosis and treatment of children with this condition.
