Control status and follow-up of acute attacks in children with bronchial asthma with normal pulmonary ventilation function
10.7499/j.issn.1008-8830.2311149
- VernacularTitle:肺通气功能正常的儿童支气管哮喘控制情况及急性发作随访的研究
- Author:
Lan-Lan MA
1
;
Ling CHEN
;
Qin WANG
;
Yang-Guang XU
;
Xing CHEN
Author Information
1. 山东第二医科大学临床医学院,山东潍坊 261053;山东第一医科大学附属省立医院小儿呼吸科,山东济南 250021
- Keywords:
Bronchial asthma;
Pulmonary ventilatory function;
Asthma control;
Child
- From:
Chinese Journal of Contemporary Pediatrics
2024;26(5):476-480
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the control status of bronchial asthma(referred to as"asthma")in school-age children with normal pulmonary ventilation function and the occurrence of acute attacks within 1 year of follow-up.Methods A retrospective analysis was conducted on clinical data of 327 children aged 6-14 years with bronchial asthma and normal pulmonary ventilation function from April to September 2021.Based on the measured value of one second rate(FEV1/FVC),the children were divided into the ≥80%group(267 cases)and the<80%group(60 cases).The pulmonary ventilation function,asthma control level,and occurrence of acute attacks within 1 year were compared between the two groups.Results The baseline pulmonary ventilation function in the<80%group was lower than that in the ≥80%group,and the proportion of small airway dysfunction was higher than that in the ≥80%group(P<0.05).After standardized treatment for 1 year,the small airway function indices in the<80%group improved but remained lower than those in the ≥80%group(P<0.05).The rate of incomplete asthma control at baseline was 34.6%(113/327),and the asthma control level in the<80%group was lower than that in the ≥80%group(P<0.05).After standardized treatment for 1 year,the asthma control level in the<80%group remained lower than that in the ≥80%group,and the proportion of acute asthma attacks was higher than that in the ≥80%group(P<0.05).Conclusions Approximately one-third of school-age children with asthma still have incomplete asthma control when their pulmonary ventilation function is normal.Among them,children with measured FEV1/FVC<80%have an increased risk of acute asthma attacks and require close follow-up and strengthened asthma management.