Pharmacological therapies for height improvement in pubertal children with short stature
10.7499/j.issn.1008-8830.2309125
- VernacularTitle:青春期矮身材儿童身高改善的药物治疗
- Author:
Jian-Fang ZHU
1
;
Chun-Lin WANG
Author Information
1. 浙江大学医学院附属第一医院儿科,浙江杭州 310003
- Keywords:
Short stature;
Recombinant human growth hormone;
Gonadotropin-releasing hormone analog;
Aromatase inhibitor;
Puberty
- From:
Chinese Journal of Contemporary Pediatrics
2024;26(2):118-123
- CountryChina
- Language:Chinese
-
Abstract:
Short stature in puberty significantly affects the physical and mental health of adolescents.The continuous acceleration of skeletal maturation,caused by sex hormones during puberty,limits the time available for growth and poses a considerable challenge for the treatment of short stature.To date,there is still no standardized treatment protocol for this disorder.However,puberty is the last period to improve the final adult height.Currently,commonly used pharmacological treatments in clinical settings include recombinant human growth hormone,gonadotropin-releasing hormone analogs,and third-generation aromatase inhibitors.In recent years,personalized treatment aiming to improve the final adult height has become a key focus in clinical practice.This article provides a comprehensive summary of research on pharmacological therapies for height improvement in pubertal children with short stature,offering valuable insights for healthcare professionals.[Chinese Journal of Contemporary Pediatrics,2024,26(2):118-123]
