Research advances in the association between apolipoprotein B/apolipoprotein A1 ratio and ischemic stroke
10.19845/j.cnki.zfysjjbzz.2024.0200
- VernacularTitle:载脂蛋白B/载脂蛋白A1比值与缺血性卒中的相关性研究进展
- Author:
Hui QIN
1
;
Xiaoyu HUANG
Author Information
1. 岳阳市中心医院,湖南岳阳 414000
- Keywords:
Apolipoprotein B/apolipoprotein A1 ratio;
Ischemic stroke;
Association;
Research advances
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(11):1047-1050
- CountryChina
- Language:Chinese
-
Abstract:
Ischemic stroke(IS)is the leading cause of neurological disability and death,and it is mainly associated with intracranial atherosclerotic stenosis.Plasma apolipoprotein B/apolipoprotein A1 ratio(ApoB/A1)can reflect the bal-ance between atherosclerosis and anti-atherosclerotic capacity and has been confirmed to be an independent risk factor for coronary heart disease.However,there are few literature reports on the association between ApoB/A1 and IS.This article reviews the biological properties of ApoB/A1,the pathophysiological mechanisms associated with atherosclerosis,and the advances in related clinical studies.