Immune-mediated necrotizing myopathy with positive anti-signal recognition particle antibody and anti-GT1a an-tibody accompanied by peripheral nerve injury:a case report
10.19845/j.cnki.zfysjjbzz.2024.0107
- VernacularTitle:伴周围神经损害的抗SRP抗体及抗GT1a抗体双阳性免疫介导坏死性肌病1例报告
- Author:
Zhongsheng ZHANG
1
;
Jiaxing HUANG
;
Xue-Jian KONG
Author Information
1. 广州医科大学附属第六医院(清远市人民医院)神经内科,广东 清远 511518
- Keywords:
Signal recognition particle;
Necrotizing myopathy;
Limb weakness
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(6):560-562
- CountryChina
- Language:Chinese
-
Abstract:
Anti-signal recognition particle(SRP)necrotizing myopathy is a type of immune-mediated necrotizing myopathy(IMNM).It is a rare disease in clinical practice and has the features of insidious onset and rapid progression,with the main manifestations of symmetrical proximal limb weakness and a significant increase in creatine kinase.This ar-ticle reports a patient with positive serum anti-SRP antibody and anti-GT1a antibody accompanied by peripheral neuropa-thy and analyze related clinical data and diagnosis and treatment processes,in order to improve the understanding of this disease among clinicians.
