Advances in the mechanism of action and clinical studies of the novel antiepileptic drug brivaracetam
10.19845/j.cnki.zfysjjbzz.2024.0096
- VernacularTitle:新型抗癫痫发作药物布瓦西坦作用机制及临床研究进展
- Author:
Lijun WAN
1
;
Xuewu LIU
Author Information
1. 山东第一医科大学附属省立医院神经内科,山东 济南 250021
- Keywords:
Epilepsy;
Brivaracetam;
Antiepileptic drugs;
Synaptic vesicular protein
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(6):507-510
- CountryChina
- Language:Chinese
-
Abstract:
Epilepsy is one of the common diseases of the nervous system,which is characterized by repeated epilep-tic seizures caused by abnormal discharge of brain neurons.Brivaracetam is an analogue of the third-generation antiepilep-tic drug levetiracetam and exerts a therapeutic effect by binding to synaptic vesicular protein 2A.This article reviews the disease of epilepsy and the mechanism of action,pharmacokinetic characteristics,clinical efficacy,safety,and adverse reactions of brivaracetam in epilepsy,in order to provide a better choice of drugs for the treatment of epilepsy.
