Role of microglial cells in ischemic stroke and related therapies
10.19845/j.cnki.zfysjjbzz.2024.0091
- VernacularTitle:小胶质细胞在缺血性脑卒中进展过程中的作用及相关治疗
- Author:
Da ZHANG
1
;
Luqing ZHAO
Author Information
1. 山西医科大学第五临床医学院神经内科,山西 太原 030000
- Keywords:
Microglial cells;
Ischemic stroke;
Treatment
- From:
Journal of Apoplexy and Nervous Diseases
2024;41(5):476-480
- CountryChina
- Language:Chinese
-
Abstract:
Stroke is an important disease that leads to disability and death in humans and has relatively high disabil-ity and mortality rates.Microglial cells,as an important component of the central nervous system,can be induced into dif-ferent phenotypes of M1 and M2 by pathological stimulation and play a dual role of neurotoxicity and neuroprotection.This article reviews the role of microglial cells in the progression of ischemic stroke and explores the new targets for the treat-ment of ischemic stroke through intervention of microglial cells.
