Research Progress on Production Processes and Quality Control Methods of Carbohydrate Drugs
10.3870/j.issn.1004-0781.2024.08.022
- VernacularTitle:糖类药物制药生产工艺及其质量控制方法研究进展
- Author:
Yuanyang WU
1
;
Zhuyu JIN
;
Shenggu XIE
;
Qian SHEN
;
Xiaoqin LIU
Author Information
1. 浙江省食品药品检验研究院,国家药品监督管理局仿制药评价关键技术重点实验室,浙江省药品接触材料质量控制研究重点实验室,杭州 310052
- Keywords:
Carbohydrate drugs;
Extraction technology;
Separation and purification;
Detection methods
- From:
Herald of Medicine
2024;43(8):1315-1320
- CountryChina
- Language:Chinese
-
Abstract:
Carbohydrates,with complex and diverse structures,exist widely in animals,plants,and microorganisms.Carbohydrates have a wide range of pharmacological activities,especially in anticoagulation,antithrombotic,blood lipid regula-tion,and immune function regulation.With the deepening of the research of carbohydrate drugs and the application of modern an-alytical technology,the detection of chemical structure,molecular weight and molecular weight distribution,and related sub-stances(impurities)of carbohydrate drugs has been developed rapidly.In this paper,the progress of carbohydrate drugs in ex-traction technology,separation and purification technology,composition analysis,content determination,and structural analysis in recent years was briefly reviewed,which provided some guidance for developing and quality control of carbohydrate drugs.
