Analysis of Prognostic Risk Factors in 507 Patients with Severe Pneumonia after Endotracheal Intubation
10.11969/j.issn.1673-548X.2024.05.022
- VernacularTitle:507例重症肺炎患者气管插管后预后危险因素分析
- Author:
Pan PAN
1
;
Qing HU
;
Tao CHENG
Author Information
1. 610041 成都,四川大学华西医院急诊科
- Keywords:
Severe pneumonia;
Endotracheal intubation;
Death;
Risk factors
- From:
Journal of Medical Research
2024;53(5):108-112
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the independent risk factors of death in patients with severe pneumonia after endotracheal intuba-tion(ETI),so as to provide clinical basis for early intervention.Methods The data of 507 patients with severe pneumonia who under-went ETI in the Department of Emergency,West China Hospital,Sichuan University from February 2018 to February 2023 were analyzed retrospectively.The outcome of the study was whether the patients died 28 days after intubation.The patients were divided into survival group and death group.The general data(age,body weight,gender,chronic disease,use of inducer before intubation,sepsis),physical and chemical indexes 12 hours after intubation and hypotension within 1 hour after intubation were compared between the two groups.Sig-nificant differences between groups were included in univariate and multivariate Logistic regression analysis to analyze the influencing fac-tors of death 28 days after endotracheal intubation in patients with severe pneumonia.Results There were significant differences in age,body weight,use of inducer before intubation,complication of chronic obstructive pulmonary disease or sepsis,increase of lactic acid after intubation and hypotension after intubation between the two groups(P＜0.05).Univariate and multivariate Logistic regression analysis showed that age,body weight,use of inducer before intubation,hyperlactic acidemia,chronic obstructive pulmonary disease,sepsis and hypotension after intubation were risk factors for death.Conclusion Age,low body weight,use of inducer before intubation,increased of lactic acid level after intubation,complication of chronic obstructive pulmonary disease or sepsis and hypotension after intubation are in-dependent risk factors for death 28 days after intubation in patients with severe pneumonia.Early clinical intervention should be carried out to improve the prognosis of patients with severe pneumonia.
