Comparison of curative effect of modified lateral approach and caudal approach in laparoscopic radical operation for colon cancer
10.3760/cma.j.cn115455-20240105-00016
- VernacularTitle:改良横向入路法与尾侧入路法腹腔镜根治术治疗结肠癌的疗效对比
- Author:
Zhiming ZHAO
1
;
Xiaojing LI
;
Liwei LI
Author Information
1. 绥化市第一医院普外二科，绥化 152000
- Keywords:
Colonic neoplasms;
Laparoscopes;
Improved transverse approach method;
Caudal approach
- From:
Chinese Journal of Postgraduates of Medicine
2024;47(10):927-931
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the curative effect of modified lateral approach and caudal approach in laparoscopic radical operation for colon cancer.Methods:A total of 100 patients undergoing colon cancer surgery in the Suihua City First Hospital from January 2020 to January 2023 were retrospectively selected as the study objects, and they were divided into two groups according to different surgical methods, 49 patients undergoing laparoscopic radical resection by caudal approach were in the control group, and 51 patients undergoing laparoscopic radical resection by modified lateral approach were in the study group. The levels of clinical related surgical indexes, tumor markers, gastrointestinal function indexes and stress response indexes were compared between the two groups, and the incidence of complications was compared between the two groups.Results:The operation time, intraoperative blood loss, number of lymph node dissection and hospital stay in the study group were lower than those in the control group: (175.48 ± 16.87) min vs. (203.12 ± 15.41) min, (104.63 ± 13.47) ml vs. (118.07 ± 15.98) ml, (18.72 ± 1.67) nodes vs. (19.96 ± 2.01) nodes, (9.13 ± 1.64) d vs. (13.48 ± 2.19) d, there were statistical differences ( P<0.05). After operation, the levels of cancer antigen 19-9 (CA199) and carcinoembryonic antigen (CEA) in the study group were lower than those in the control group: (37.16 ± 9.24) kU/L vs. (42.14 ± 10.23) kU/L, (18.27 ± 6.76) μg/L vs. (22.45 ± 8.45) μg/L, there were statistical differences ( P<0.05). The postoperative exhaust time, feeding time and bowel sound recovery time in the study group were shorter than those in the control group: (40.47 ± 5.03) h vs. (59.73 ± 6.16) h, (70.58 ± 8.24) h vs. (94.57 ± 10.42) h, (21.79 ± 3.68) h vs. (35.06 ± 4.27) h, there were statistical differences ( P<0.05). After operation, the levels of adrenocorticotropin (ACTH), aldosterone (ALD) and cortisol (Cor) in the study group were lower than those in the control group: (16.95 ± 1.91) ng/L vs. (21.52 ± 2.53) ng/L, (135.00 ± 15.24) ng/L vs. (151.80 ± 15.72) ng/L, (220.03 ± 21.40) μg/L vs. (239.94 ± 24.37) μg/L, there were statistical differences ( P<0.05). The incidence of surgical complications in the study group was lower than that in the control group: 5.88%(3/51) vs. 22.45%(11/49), there was statistical difference ( χ2 = 11.60, P<0.05). Conclusions:The therapeutic effect of modified transverse approach radical laparoscopy is higher than that of caudal approach radical laparoscopy.
