Risk factors of continuous blood purification extracorporeal circulation apparatus plugging without anticoagulation
10.3760/cma.j.issn.1674-2907.2019.34.001
- VernacularTitle:无抗凝连续性血液净化治疗体外循环装置堵塞危险因素分析
- Author:
Zhonghua ZHANG
1
;
Tieying ZENG
;
Rong XU
;
Jianjun YAN
;
Hui TONG
;
Gang XU
Author Information
1. 华中科技大学同济医学院附属同济医院血液净化中心,武汉 430030
- Keywords:
Extracorporeal circulation;
Without anticoagulation;
Continuous blood purification;
Apparatus plugging
- From:
Chinese Journal of Modern Nursing
2019;25(34):4405-4411
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the risk factors of continuous blood purification (CBP) extracorporeal circulation apparatus plugging without anticoagulation. Methods From May 2014 to May 2018, data from 257 patients with CBP without anticoagulation for the first time in Blood Purification Center at Tongji Hospital were retrospectively collected. The data included patients' general demographic data, apparatus types, areas and materials of membrane, types of blood access, treatment models, apparatus use time, whether infusing concentrated red cell, whether washing with 0.9% sodium chloride solution periodically, frequencies of nursing intervention when poor blood flow, laboratory data 24 hours before treatment, immediate transmembrane pressure gradient and venous pressure when apparatus plugging. The simple correlation and multivariate Cox proportional hazard regression model were used to analyze the risk factors of CBP extracorporeal circulation apparatus plugging without anticoagulation. Results Among those 257 patients, the use time of extracorporeal circulation apparatus was (248.51±87.56) min with 48.64% for the incidence of plugging. Multivariate Cox proportional hazard regression model showed that the risk factors of CBP extracorporeal circulation apparatus plugging included the high volume ratio of blood coagulation in the vein pot (HR: 1.024, 95%CI: 1.016-1.032), high frequency of nursing intervention when poor blood flow (HR: 1.600, 95%CI: 1.381-1.852) and high hematocrit (HR: 1.047, 95%CI: 1.003-1.094) with statistical differences (P＜0.05). Conclusions CBP extracorporeal circulation apparatus plugging without anticoagulation has correlations with the volume ratio of blood coagulation in the vein pot, frequency of nursing intervention when poor blood flow and patients' hematocrit.
