Laparoscopy and/or Hysteroscopy in Differential Diagnosis and Treatment of Suspected Gestational Trophoblastic Neoplasia
10.3969/j.issn.1674-9081.2016.04.003
- VernacularTitle:腹腔镜和／或宫腔镜在疑诊妊娠滋养细胞肿瘤患者鉴别诊断和治疗中的应用
- Author:
Yu GU
1
;
Feng-Zhi FENG
;
Yang XIANG
;
Xi-Run WAN
;
Tong REN
;
Jun-Jun YANG
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院妇产科
- Keywords:
gestational trophoblastic neoplasia;
laparoscopy;
hysteroscopy;
diagnosis
- From:
Medical Journal of Peking Union Medical College Hospital
2016;7(4):253-258
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the application of laparoscopy and /or hysteroscopy in differential di-agnosis and treatment of suspected gestational trophoblastic neoplasia (GTN), and its potential impact on out-come.Methods From January 2005 to December 2013, 160 patients with a suspected diagnosis of GTN were admitted to Peking Union Medical College Hospital and underwent laparoscopy and /or hysteroscopy for it .The clinical data , diagnosis , and outcome of these patients were retrospectively analyzed .Results Among the 160 eligible patients , 26 were confirmed with GTN , including choriocarcinoma in 15 cases , invasive mole in 6 cases , and placental site trophoblastic tumor (PSTT) in 5 cases.The diagnosis of GTN was ruled out in the other 134 ca-ses, including intrauterine gestational residues in 106 (51 cases of incomplete abortion , 52 cases of residues of cor-nual pregnancy , 2 cases of placental remnants , 1 case of residual hydatidiform mole ) , cesarean scar pregnancy in 23, cornual pregnancy in 3, intramural pregnancy in 2.There was no significant difference in most of the clini-cal data between GTN patients and non-GTN patients except for the type of last pregnancy ( P<0.001 ) .All of the GTN and the non-GTN patients achieved complete remission or cure by subsequent chemotherapy or surgical therapy except one patient lost to follow-up during the course of the treatment .Conclusions Laparoscopy and/or hysteroscopy could be an effective strategy to facilitate diagnosis when it is difficult to differentiate GTN from non -GTN diseases by clinical data .Furthermore, that technique would not affect the outcome for GTN patients , while for non-GTN patients they could offer effective treatment .
