Guillain-Barre syndrome after allogeneic hematopoietic stem cell transplantation: a case report and literature review
10.3760/cma.j.cn121090-20231020-00222
- VernacularTitle:异基因造血干细胞移植后合并吉兰-巴雷综合征1例报告并文献复习
- Author:
Yajun SHI
1
;
Ying HAN
;
Ying WANG
;
Rui ZHOU
;
Rui SONG
;
Dongfeng MAO
;
Rui XI
;
Hai BAI
;
Tao WU
Author Information
1. 中国人民解放军联勤保障部队第九四〇医院血液科，兰州 730050
- From:
Chinese Journal of Hematology
2024;45(5):509-511
- CountryChina
- Language:Chinese
-
Abstract:
Guillain-Barre syndrome rarely develops after allogeneic hematopoietic stem cell transplantation (allo-HSCT), and only a few reports exist in China. Guillain-Barre syndrome is an acute and life-threatening condition that requires early diagnosis and treatment. A patient with acute myeloid leukemia underwent allogeneic HSCT for >5 months and gradually developed limb muscle weakness and limited eye movement after coexisting with delayed acute intestinal graft-versus-host disease. After the examination of cerebrospinal fluid and electromyography, the diagnosis of Guillain–Barre syndrome was confirmed. After a high-dose intravenous immunoglobulin (IVIg) treatment, muscle strength gradually recovered, and the prognosis was good.
