Research advances in the treatment of keloid with glucocorticoids
	    		
		   		
		   			
		   		
	    	
    	 
    	10.3760/cma.j.cn501225-20230602-00198
   		
        
        	
        		- VernacularTitle:糖皮质激素治疗瘢痕疙瘩的研究进展
 
        	
        	
        	
        		- Author:
	        		
		        		
		        		
			        		Yinghong SU
			        		
			        		
			        		
			        			1
			        			
			        		
			        		
			        		
			        		
			        		;
		        		
		        		
		        		
			        		Wenzheng XIA
			        		
			        		;
		        		
		        		
		        		
			        		Xin HUANG
			        		
			        		;
		        		
		        		
		        		
			        		Ruoqing XU
			        		
			        		;
		        		
		        		
		        		
			        		Khoong YIMIN
			        		
			        		;
		        		
		        		
		        		
			        		Tao ZAN
			        		
			        		
		        		
		        		
		        		
		        		
		        			
			        		
			        		Author Information
			        		
		        		
		        		
			        		
			        		
			        			1. 上海交通大学医学院附属第九人民医院整复外科,上海 200011
			        		
		        		
	        		
        		 
        	
        	
        	
        	
        		- Keywords:
        			
	        			
	        				
	        				
			        		
				        		Keloid;
			        		
			        		
			        		
				        		Glucocorticoids;
			        		
			        		
			        		
				        		Receptors, glucocorticoid;
			        		
			        		
			        		
				        		Drug resistance
			        		
			        		
	        			
        			
        		
 
        	
            
            
            	- From:
	            		
	            			Chinese Journal of Burns
	            		
	            		 2023;39(9):886-890
	            	
            	
 
            
            
            	- CountryChina
 
            
            
            	- Language:Chinese
 
            
            
            	- 
		        	Abstract:
			       	
			       		
				        
				        	As a first-line classical drug, glucocorticoids are used in most combination treatment regimens of keloid. However, there are issues such as poor treatment efficacy and recurrence of keloid after keloid was treated with glucocorticoids, which seriously affect the therapeutic effect. In recent years, many studies have explored the factors influencing the efficacy of glucocorticoids in treating keloid and the action mechanism of glucocorticoids from different perspectives. Based on this, this paper reviews the mechanism and the factors influencing the efficacy of glucocorticoids in treating keloid, and explores ways to improve the treatment efficacy of glucocorticoids, aiming to provide thoughts for improving glucocorticoid-related diagnostic and therapeutic strategies.