Research advances of sepsis biomarkers
10.3760/cma.j.cn501225-20230320-00086
- VernacularTitle:脓毒症生物标志物的研究进展
- Author:
Zhuo ZENG
1
;
Yizhi PENG
;
Zhiqiang YUAN
Author Information
1. 陆军军医大学(第三军医大学)第一附属医院,全军烧伤研究所,创伤、烧伤与复合伤 国家重点实验室,重庆 400038
- Keywords:
Sepsis;
Diagnosis;
Prognosis;
Biomarker
- From:
Chinese Journal of Burns
2023;39(7):679-684
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is a life-threatening condition for patients. Biomarkers can be used for the diagnosis, treatment, and prognostic assessment of sepsis. In recent years, new biomarkers for sepsis have been discovered, and more than 250 biomarkers have been identified so far. The complexity of the sepsis process and the increased sensitivity of various detection techniques will lead to the emergence of new biomarkers. However, there is still a lack of specific diagnostic biomarkers and effective therapeutic approaches for sepsis in clinical practice. Therefore, the search for reliable biomarkers and the evaluation of the role of biomarkers in sepsis will undoubtedly aid in clinical decision-making. This article reviews the advances on research of sepsis biomarkers in order to improve understanding of current biomarkers of sepsis, and provide reference for the application of biomarkers in clinical diagnosis, treatment, and prognosis of sepsis.