Update of pathology in medullary thyroid carcinoma
10.16139/j.1007-9610.2023.06.03
- VernacularTitle:甲状腺髓样癌病理诊断新进展
- Author:
Zhiyan LIU
1
;
Yaling YU
;
Kennichi KAKUDO
Author Information
1. 上海交通大学医学院附属第六人民医院病理科,上海 200233
- Keywords:
Medullary thyroid carcinoma;
Histologic grading scheme;
Genetic screening;
Genetic counseling
- From:
Journal of Surgery Concepts & Practice
2023;28(6):501-506
- CountryChina
- Language:Chinese
-
Abstract:
Medullary thyroid carcinoma(MTC)is a rare thyroid malignancy,which is more aggressive with high metastasis and recurrence rate.Surgical treatment is the preferred treatment option for MTC.Targeted therapy and immunotherapy have gradually become new treatment strategy for MTC.The pathology of MTC was updated in the 5th edition WHO classification of endocrine and neuroendocrine tumor in 2022.This review summarized the update of MTC pathology focusing on the histologic grading schemes,gene screening and genetic counseling.
