Study on the Influencing Factors of Postoperative Recurrence of Vocal Cord Leukoplakia and the Establishment of Predictive Model
10.3969/j.issn.1006-7299.2024.04.008
- VernacularTitle:声带白斑术后复发影响因素探究及预测模型的建立
- Author:
Huanhuan WANG
1
;
Yanrong ZHENG
;
Limin WANG
Author Information
1. 首都医科大学附属北京友谊医院耳鼻咽喉头颈外科(北京 100050)
- Keywords:
Vocal cord leukoplakia;
Postoperative recurrence;
Risk factors;
Predictive model
- From:
Journal of Audiology and Speech Pathology
2024;32(4):326-329
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the influencing factors of postoperative recurrence of vocal cord leukoplakia and establish a clinical prediction model.Methods A total of 386 patients with vocal cord leukoplakia treated in our hospital from February 2016 to February 2020 were selected retrospectively.According to the follow-up results,the patients were divided into two groups:recurrent group(n=89)and non-recurrent group(n=297).The general and clinical data of the two groups were collected.The influencing factors of postoperative recurrence of vocal cord leu-koplakia were screened by univariate analysis and Logistic regression analysis,and the Logistic risk prediction model was established.The model was internally verified by R software and boostrap method.Results Age(OR=0.924),drinking history(OR=1.946),voice abuse(OR=2.436),laryngopharyngeal reflux(OR=0.487),mod-erate dysplasia(OR=0.420)and severe dysplasia(OR=0.303)were the influencing factors of postoperative recur-rence of vocal cord leukoplakia.The internal verification AUC of the model was 0.777,95％the confidence interval was 0.663～0.825,and the model fit well.Conclusion The postoperative recurrence of vocal cord leukoplakia is related to the patient's age,leukoplakia range,pathological morphology and laryngopharyngeal reflux.
