Connective tissue disease-associated interstitial lung disease:from pathogenesis to"dual-target"treatment strategies
- VernacularTitle:结缔组织病相关间质性肺病:从发病机制研究到"双达标"治疗策略
- Author:
Mengtao LI
1
;
Qian WANG
Author Information
- Keywords: connective tissue diseases; lung diseases,interstitial; diagnosis; therapy; pathogenesis
- From: Tianjin Medical Journal 2024;52(7):673-678
- CountryChina
- Language:Chinese
- Abstract: Connective tissue diseases(CTD)are a spectrum of heterogeneous diseases with multiple organ involvements.Interstitial lung diseases(ILD)are serious complications of CTD.There is great heterogeneity in pathogenesis,clinical manifestations,and treatment of different CTD-ILD.Previous basic and clinical studies have explored the pathogenesis of CTD-ILD,and the"dual-target"treatment strategy has therefore emerged.The implementation of the"dual-target"treatment strategy helps to control CTD activity and lung inflammation in the early stage,prevent the progression of pulmonary fibrosis,and thus improve patient survival and quality of life.
