Study of Ultrasound-guided Fine Needle Aspiration for Cellular Pathological Diagnosis of Thyroid Papillary Cancer
10.3870/j.issn.1672-0741.24.03.006
- VernacularTitle:超声引导下细针吸取细胞病理学诊断甲状腺乳头状癌的临床研究
- Author:
Qi LIU
1
;
Jinsong KANG
;
Heng MA
Author Information
1. 华中科技大学同济医学院附属同济医院肿瘤科,武汉 430030
- Keywords:
fine needle aspiration cytology;
ultrasound-guided;
papillary thyroid carcinoma;
BRAF V600E mutation
- From:
Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
2024;53(5):676-680
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical significance of ultrasound-guided fine needle aspiration cytology in the diagno-sis of papillary thyroid carcinoma.Methods For cases of thyroid nodules with a diameter less than 1 cm and negative clinical palpation detected by ultrasound,ultrasound-guided fine needle aspiration cytological examination was performed,and the cyto-logical results were compared and analyzed with postoperative histopathological results and BRAFV600E detection re-sults.Results Among the 511 cases,the cytopathological results showed 20 cases of failed sampling,14 cases of benign lesions,230 cases of suspected malignancy,242 cases of papillary thyroid carcinoma,2 cases of non-Hodgkin's lymphoma,and 3 cases of medullary thyroid carcinoma.The histopathological results showed 5 benign cases,496 papillary thyroid carcinoma,3 papillary thyroid carcinoma with Hashimoto's thyroiditis,3 non-Hodgkin's lymphoma,and 4 medullary thyroid carcinoma.There were 10 false negative cases in cellular pathology,with no false positive cases.The consistency rate between cellular pathology and histopathology was 94.27％.Conclusion Ultrasound-guided fine needle aspiration cytology has a high diagnostic accuracy for papilla-ry thyroid carcinoma,and provides accurate results for clinical palpation negative masses before surgery.Combined with postoperative histopathology and BRAFV600E gene testing results,it provides a strategy for subsequent treatment and follow-up.
