Challenges and optimization strategies for clinical research and the development of new drugs for liver fibrosis
10.3760/cma.j.cn501113-20240226-00095
- VernacularTitle:肝纤维化新药临床研发的挑战及其优化策略
- Author:
Xiaobo CAI
1
;
Ying QU
;
Lungen LU
Author Information
1. 上海交通大学医学院附属第一人民医院消化内科，上海 200080
- Keywords:
Liver fibrosis;
New drugs;
Research and development
- From:
Chinese Journal of Hepatology
2024;32(4):303-305
- CountryChina
- Language:Chinese
-
Abstract:
Liver fibrosis is a key step in the developmental process of various chronic liver diseases, including cirrhosis. Therefore, the focus and difficulty of liver disease research have always been on how to reverse liver fibrosis. However, due to complex mechanisms, difficulties in endpoint evaluation, a lack of non-invasive diagnostic methods, and other factors, the research and development of new drugs are hindered and lengthy. Currently, some new drugs are being researched and developed, which signifies the prospect is optimistic.
