Research progress of signal pathways related to the anti-tumor effect of Astragalin
10.11904/j.issn.1002-3070.2024.01.010
- VernacularTitle:紫云英苷抗肿瘤作用相关信号通路的研究进展
- Author:
Ding XIAO
1
;
Juncheng BAI
;
Bin ZHANG
Author Information
1. 内蒙古民族大学临床医学院(通辽 028000);内蒙古民族大学附属医院心脏、血管外科
- Keywords:
Astragalin;
Anti-tumor;
Signaling pathway
- From:
Practical Oncology Journal
2024;38(1):62-66
- CountryChina
- Language:Chinese
-
Abstract:
Astragalin is a natural flavonoid,which is known for its diverse pharmacological applications such as anti-tumor.The many studies have found that Astragalin has great anti-tumor potential by regulating PI3K/Akt signal pathway,MAPKs signal pathway,JAK/STAT signal pathway,NF-κ B signal pathway,Notch1 pathway,microRNA expression,tumor invasion and metastasis.This article reviews the literature reports on anti-tumor signal pathway of Astragalin in recent years,analyzes and summarizes the pos-sible mechanisms by which each pathway induces tumor cell apoptosis,in order to provide experimental and theoretical basis for the development and utilization of Astragalin in anti-tumor signal pathways.
