Clinicopathological characteristics and key therapeutic options for liver involvement with vasculitis
10.3760/cma.j.cn501113-20230813-00053
- VernacularTitle:血管炎肝脏受累的临床病理特点及治疗要点
- Author:
Suyun CHEN
1
;
Xinyan ZHAO
Author Information
1. 福建省儿童医院小儿外科，福州 350005
- Keywords:
Antineutrophil cytoplasmic antibody;
Cholestasis;
Portal hypertension;
Vascular diseases of the liver
- From:
Chinese Journal of Hepatology
2023;31(9):905-909
- CountryChina
- Language:Chinese
-
Abstract:
Vasculitis, involving any levels of vessels throughout the body, has variable nonspecific clinical presentation and complicated classification, hence, the diagnose is difficult. The liver is not the major organ involved, so it is prone to overlook vasculitis-associated liver injuries. The main manifestations of vasculitis involving the liver include abnormal liver biochemistry test (mainly increase of cholestatic liver enzymes), portal hypertension, and hepatic occupying lesions. Treatment principles are primarily directed at systemic immunosuppressive therapy for vasculitis. This review summarized the classification of vasculitis, major presentations of liver involvement in vasculitis, and the principles of treatment, to improve the awareness of the rare vascular diseases.
